The Wonder of Nitric Oxide

Clinically proven to safely and effectively kill viruses and bacteria.

Nitric oxide is a powerful, naturally occurring molecule that plays a critical role in supporting your immune defense and promoting overall health. Its antiviral and antimicrobial properties help protect against common infections and illnesses.

Proven, Natural Protection

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    Safe

    Nitric oxide has been studied extensively and proven to be a safe agent for improving immune function without the risk of harmful side effects.

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    Effective

    Clinical studies demonstrate that nitric oxide inhibits the replication of harmful viruses, including influenza and SARS-CoV-2, showcasing its powerful antiviral capabilities.

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    Natural

    A natural part of your immune system, nitric oxide works in harmony with your body’s natural defenses to provide vital support in the fight against infections and promote overall well-being.
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Badge for Molecule of the Year

Molecule of the Year 1992

Science Journal, 1992

In recognition of nitric oxide’s crucial role as a signaling molecule in the body, regulating vital functions like blood pressure, immune response, and nerve signaling. Nitric oxide is also involved in the regulation of inflammation and may have direct antimicrobial effects against viruses, fungi, and bacteria.

References:

  • Rimmelzwaan GF, Baars MMJW, De Lijster P, et al. Inhibition of Influenza Virus Replication by Nitric Oxide. Journal of Virology 1999; 73:8880-8883.
  • Schairer AO, Chouake JS, Nosanchuk JD, et al. The potential of nitric oxide releasing therapies as antimicrobial agents. Virulence 2012; 3:271-279.
  • Tandon M, Wu W, Moore K, et al. SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial. The Lancet Regional Health – Southeast Asia 2022; 3:1-14.
  • Croen KD. Evidence for antiviral effect of nitric oxide. Inhibition of herpes simplex virus type 1 replication. The Journal of Clinical Investigation 1993; 91:2446-2452.
  • Garren MR, Ashcraft M, Qian Y, et al. Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms. Applied Materials Today 2021; 22:1-16.
  • Bath PM, Coleman CM, Gordon A, et al. Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 2; peer review: 1 approved, 2 approved with reservations]. Research 2021; 10:536.
  • Levine AB, Punihaole D, Levine TB, et al. Characterization of the Role of Nitric Oxide and Its Clinical Applications. Cardiology 2012; 122:55-68.
  • Akertstrom S, Gunalan V, Keng CT, et al. Dual effect of nitric oxide on SARS-CoV replication: Viral RNA production and palmitoylation of the S protein are affected. Virology 2009; 395:1-9.

This information on The Science of Nitric Oxide is provided for information purposes and is not intended to relate to any specific product. None of the uses described on this website for the various forms of NOWONDER™ products are intended to make therapeutic or prevention claims. These products are intended as part of skin, nail, or foot care regimens, and are not intended to treat or prevent disease conditions. These are not drugs or medical device products and no claims have been reviewed by the Food and Drug Administration.